Study: Pioglitazone halts progression to type 2 diabetes

In a new study, pioglitazone reduced the risk for progression from impaired glucose tolerance to type 2 diabetes by 72% as compared with placebo. However, the drug was linked to significant edema and weight gain. Ralph A. DeFronzo, MD, and colleagues recruited 602 adults with IGT to study whether pioglitazone (Actos, Takeda) could reduce the [...]

Reversing diabetes is possible

That was two years ago. Since that time, the Morgan Stanley executive decided to make some changes and reverse his diabetes. Although his doctor recommended he go on medication to control his illness, Legg took a different approach. Instead of meds, he began to exercise every day and changed his diet, cutting out alcohol, fatty foods and watching his carbs.

Q&A: Alzheimer’s trial disconnect

While preclinical studies identify ways to prevent Alzheimer’s disease in animals, human trials test these same therapies in symptomatic patients — long after they are most likely to be effective

Uncontrolled hypertension, chronic kidney disease may increase retinopathy risk

High blood pressure and chronic kidney disease are associated with a higher incidence of retinopathy in subjects who are not diabetic, a study found. The 15-year cumulative incidence of retinopathy in the Beaver Dam Eye Study was 14.2% in 4,699 subjects between the ages of 43 years and 86 years. Subjects with uncontrolled hypertension had [...]

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