Epigenetic Changes in Cancer

Distinctive cancer-associated patterns of CpG island hypermethylation are tumor type-specific and contribute decisively to the origin and development of human cancer.

Pfizer Drug Targets Gene Flaw to Shrink Lung Tumors (Update1)

An experimental pill from Pfizer Inc. shrank tumors in patients with a rare form of lung cancer that is caused by a defective gene and occurs mostly in nonsmokers, a study showed. The medicine, crizotinib, reduced tumor size in 57 percent of patients and stopped the progression of the disease in 87 percent of those [...]

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